MRPS34

GENE INFORMATION

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Gene name

MRPS34 (HGNC Symbol)

Synonyms

MGC2616, MRP-S12

Description

Mitochondrial ribosomal protein S34 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

1771890 - 1773155

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000074071 (version 78.38)

Entrez gene

65993

UniProt

P82930 (UniProt - Evidence at protein level)

neXtProt

NX_P82930

Antibodypedia

MRPS34 antibodies
 

PROTEIN VIEW

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MRPS34-001
 
MRPS34-002
 
MRPS34-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS34-001 ENSP00000380531
ENST00000397375
P82930
Show all »
Show » Show » 218 25.7 No 0
MRPS34-002 ENSP00000177742
ENST00000177742
C9JJ19
Show all »
Show » Show » 225 26.3 No 0
MRPS34-201 ENSP00000479049
ENST00000613089
Show » 176 20.7 No 0