ENO1

GENE INFORMATION

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Gene name

ENO1 (HGNC Symbol)

Synonyms

ENO1L1, MBP-1, MPB1, PPH

Description

Enolase 1, (alpha) (HGNC Symbol)

Entrez gene summary

This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. [provided by RefSeq, Jan 2011]

Chromosome

1

Cytoband

p36.23

Chromosome location (bp)

8861002 - 8879249

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000074800 (version 78.38)

Entrez gene

2023

UniProt

P06733 (UniProt - Evidence at protein level)

neXtProt

NX_P06733

Antibodypedia

ENO1 antibodies
 

PROTEIN VIEW

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ENO1-001
 
ENO1-004
 
ENO1-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ENO1-001 ENSP00000234590
ENST00000234590
P06733
Show all »
Show » Show » 434 47.2 No 0
ENO1-004 ENSP00000466406
ENST00000497492
K7EM90
Show all »
Show » Show » 195 21 No 0
ENO1-008 ENSP00000468392
ENST00000489867
Show » 18 2.1 No 0