PAX2

GENE INFORMATION

? »

Gene name

PAX2

Synonyms

Description

Paired box 2 (HGNC Symbol)

Entrez gene summary

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor suppressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]

Chromosome

10

Cytoband

q24.31

Chromosome location (bp)

100735603 - 100829941

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000075891 (version 78.38)

Entrez gene

5076

UniProt

Q02962 (UniProt - Evidence at protein level)

neXtProt

NX_Q02962

Antibodypedia

PAX2 antibodies
 

PROTEIN VIEW

? »
 
 
 
PAX2-001
 
PAX2-002
 
PAX2-003
 
PAX2-005
 
PAX2-006
 
PAX2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAX2-001 ENSP00000347385
ENST00000355243
Q02962
Show all »
Show » Show » 394 42.2 No 0
PAX2-002 ENSP00000359319
ENST00000370296
Q02962
Show all »
Show » Show » 396 42 No 0
PAX2-003 ENSP00000398652
ENST00000427256
Q5SZP1
Show all »
Show » Show » 214 23 No 0
PAX2-005 ENSP00000452489
ENST00000554172
Q6YFJ8
Show all »
Show » Show » 304 32.4 Yes 0
PAX2-006 ENSP00000355069
ENST00000361791
Show » Show » 393 42.2 No 0
PAX2-201 ENSP00000396259
ENST00000428433
Q02962
Show all »
Show » Show » 417 44.7 No 0