FGF20

GENE INFORMATION

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Gene name

FGF20

Synonyms

Description

Fibroblast growth factor 20 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]

Chromosome

8

Cytoband

p22

Chromosome location (bp)

16992169 - 17002181

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000078579 (version 78.38)

Entrez gene

26281

UniProt

Q9NP95 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP95

Antibodypedia

FGF20 antibodies
 

PROTEIN VIEW

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FGF20-001
 
FGF20-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF20-001 ENSP00000180166
ENST00000180166
Q9NP95
Show all »
Show » Show » 211 23.5 No 0
FGF20-002 ENSP00000428072
ENST00000519941
Show » Show » 113 12.7 No 0