TOLLIP

GENE INFORMATION

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Gene name

TOLLIP (HGNC Symbol)

Synonyms

IL-1RAcPIP

Description

Toll interacting protein (HGNC Symbol)

Entrez gene summary

This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [provided by RefSeq, Aug 2011]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

1274371 - 1309654

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000078902 (version 78.38)

Entrez gene

54472

UniProt

Q9H0E2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H0E2

Antibodypedia

TOLLIP antibodies
 

PROTEIN VIEW

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TOLLIP-001
 
TOLLIP-002
 
TOLLIP-003
 
TOLLIP-004
 
TOLLIP-005
 
TOLLIP-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TOLLIP-001 ENSP00000314733
ENST00000317204
Q9H0E2
Show all »
Show » Show » 274 30.3 No 0
TOLLIP-002 ENSP00000434035
ENST00000527886
Q9H0E2
Show all »
Show » Show » 205 22.8 No 0
TOLLIP-003 ENSP00000432668
ENST00000525159
F2Z2Y8
Show all »
Show » Show » 213 23.3 No 0
TOLLIP-004 ENSP00000263646
ENST00000263646
E7EN89
Show all »
Show » Show » 246 27 No 0
TOLLIP-005 ENSP00000434494
ENST00000530541
E9PQ25
Show all »
Show » Show » 186 20.5 No 0
TOLLIP-012 ENSP00000432778
ENST00000527938
E9PNS3
Show all »
Show » 80 8.7 No 0