CDH17

GENE INFORMATION

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Gene name

CDH17 (HGNC Symbol)

Synonyms

cadherin, HPT-1

Description

Cadherin 17, LI cadherin (liver-intestine) (HGNC Symbol)

Entrez gene summary

This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]

Chromosome

8

Cytoband

q22.1

Chromosome location (bp)

94127171 - 94217303

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000079112 (version 78.38)

Entrez gene

1015

UniProt

Q12864 (UniProt - Evidence at protein level)

neXtProt

NX_Q12864

Antibodypedia

CDH17 antibodies
 

PROTEIN VIEW

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CDH17-001
 
CDH17-002
 
CDH17-003
 
CDH17-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH17-001 ENSP00000027335
ENST00000027335
Q12864
Show all »
Show » Show » 832 92.2 Yes 1
CDH17-002 ENSP00000392811
ENST00000441892
E7EN24
Show all »
Show » Show » 580 64.2 Yes 0
CDH17-003 ENSP00000401468
ENST00000450165
Q12864
Show all »
Show » Show » 832 92.2 Yes 1
CDH17-004 ENSP00000428189
ENST00000521491
E5RJT3
Show all »
Show » Show » 147 16.6 Yes 0