ARG2

GENE INFORMATION

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Gene name

ARG2

Synonyms

Description

Arginase 2 (HGNC Symbol)

Entrez gene summary

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q24.1

Chromosome location (bp)

67619798 - 67651720

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000081181 (version 78.38)

Entrez gene

384

UniProt

P78540 (UniProt - Evidence at protein level)

neXtProt

NX_P78540

Antibodypedia

ARG2 antibodies
 

PROTEIN VIEW

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ARG2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARG2-001 ENSP00000261783
ENST00000261783
P78540
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