CDC14B

GENE INFORMATION

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Gene name

CDC14B (HGNC Symbol)

Synonyms

Cdc14B1, Cdc14B2, CDC14B3, hCDC14B

Description

Cell division cycle 14B (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

Chromosome location (bp)

96490241 - 96619830

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000081377 (version 78.38)

Entrez gene

8555

UniProt

O60729 (UniProt - Evidence at protein level)

neXtProt

NX_O60729

Antibodypedia

CDC14B antibodies
 

PROTEIN VIEW

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CDC14B-001
 
CDC14B-003
 
CDC14B-004
 
CDC14B-006
 
CDC14B-009
 
CDC14B-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC14B-001 ENSP00000400480
ENST00000415608
Q5JU07
Show all »
Show » 228 26.3 No 0
CDC14B-003 ENSP00000364389
ENST00000375241
O60729
Show all »
Show » Show » 498 56.8 No 0
CDC14B-004 ENSP00000364388
ENST00000375240
O60729
Show all »
Show » Show » 459 52.8 No 0
CDC14B-006 ENSP00000420572
ENST00000463569
O60729
Show all »
Show » Show » 485 55.7 No 1
CDC14B-009 ENSP00000396951
ENST00000452280
Show » 269 31.2 No 0
CDC14B-010 ENSP00000364390
ENST00000375242
O60729
Show all »
Show » Show » 461 52.3 No 0