EPS15

GENE INFORMATION

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Gene name

EPS15 (HGNC Symbol)

Synonyms

AF-1P, MLLT5

Description

Epidermal growth factor receptor pathway substrate 15 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]

Chromosome

1

Cytoband

p32.3

Chromosome location (bp)

51354263 - 51519328

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000085832 (version 78.38)

Entrez gene

2060

UniProt

P42566 (UniProt - Evidence at protein level)

neXtProt

NX_P42566

Antibodypedia

EPS15 antibodies
 

PROTEIN VIEW

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EPS15-001
 
EPS15-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPS15-001 ENSP00000360798
ENST00000371733
P42566
Show all »
Show » Show » 896 98.7 Yes 0
EPS15-002 ENSP00000360795
ENST00000371730
B1AUU8
Show all »
Show » Show » 762 83.7 Yes 0