CEACAM6

GENE INFORMATION

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Gene name

CEACAM6 (HGNC Symbol)

Synonyms

CD66c, NCA

Description

Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

41750977 - 41772208

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000086548 (version 78.38)

Entrez gene

4680

UniProt

P40199 (UniProt - Evidence at protein level)

neXtProt

NX_P40199

Antibodypedia

CEACAM6 antibodies
 

PROTEIN VIEW

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CEACAM6-001
 
CEACAM6-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEACAM6-001 ENSP00000199764
ENST00000199764
P40199
Show all »
Show » Show » 344 37.2 Yes 1
CEACAM6-002 ENSP00000469752
ENST00000595740
M0QYD3
Show all »
Show » 33 3.7 No 0