FTL

GENE INFORMATION

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Gene name

FTL (HGNC Symbol)

Synonyms

MGC71996, NBIA3

Description

Ferritin, light polypeptide (HGNC Symbol)

Entrez gene summary

This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

48965301 - 48966878

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000087086 (version 78.38)

Entrez gene

2512

UniProt

P02792 (UniProt - Evidence at protein level)

neXtProt

NX_P02792

Antibodypedia

FTL antibodies
 

PROTEIN VIEW

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FTL-001
 
FTL-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FTL-001 ENSP00000366525
ENST00000331825
P02792
Show all »
Show » Show » 175 20 No 0
FTL-201 ENSP00000484043
ENST00000622577
Q6S4P3
Show all »
Show » Show » 190 21.2 No 0