MAVS

GENE INFORMATION

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Gene name

MAVS (HGNC Symbol)

Synonyms

Cardif, IPS-1, KIAA1271, VISA

Description

Mitochondrial antiviral signaling protein (HGNC Symbol)

Entrez gene summary

This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

3846799 - 3876123

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000088888 (version 78.38)

Entrez gene

57506

UniProt

Q7Z434 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z434

Antibodypedia

MAVS antibodies
 

PROTEIN VIEW

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MAVS-001
 
MAVS-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAVS-001 ENSP00000401980
ENST00000428216
Q7Z434
Show all »
Show » Show » 540 56.5 No 1
MAVS-201 ENSP00000413749
ENST00000416600
Q7Z434
Show all »
Show » Show » 399 40.5 No 1