NRCAM

GENE INFORMATION

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Gene name

NRCAM (HGNC Symbol)

Synonyms

Bravo, KIAA0343

Description

Neuronal cell adhesion molecule (HGNC Symbol)

Entrez gene summary

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q31.1

Chromosome location (bp)

108147623 - 108456717

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000091129 (version 78.38)

Entrez gene

4897

UniProt

Q92823 (UniProt - Evidence at protein level)

neXtProt

NX_Q92823

Antibodypedia

NRCAM antibodies
 

PROTEIN VIEW

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 « 
 
NRCAM-001
 
NRCAM-003
 
NRCAM-005
 
NRCAM-006
 
NRCAM-011
 
NRCAM-015
 
NRCAM-016
 
NRCAM-017
 
NRCAM-018
 
NRCAM-201
 
NRCAM-202
 
NRCAM-203
 
NRCAM-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NRCAM-001 ENSP00000368310
ENST00000379024
Q92823
Show all »
Show » Show » 1192 131.7 Yes 1
NRCAM-003 ENSP00000325269
ENST00000351718
Q92823
Show all »
Show » Show » 1183 131 Yes 1
NRCAM-005 ENSP00000390421
ENST00000417701
C9JH43
Show all »
Show » Show » 431 48 Yes 0
NRCAM-006 ENSP00000401244
ENST00000425651
Q92823
Show all »
Show » Show » 1304 143.9 Yes 1
NRCAM-011 ENSP00000398174
ENST00000445634
Show » 190 20.6 No 1
NRCAM-015 ENSP00000397544
ENST00000419936
C9J8B6
Show all »
Show » Show » 106 11.8 Yes 0
NRCAM-016 ENSP00000408203
ENST00000456431
C9J8B6
Show all »
Show » Show » 106 11.8 Yes 0
NRCAM-017 ENSP00000390868
ENST00000442580
C9JF43
Show all »
Show » Show » 118 13.3 Yes 0
NRCAM-018 ENSP00000393663
ENST00000418239
C9JUR7
Show all »
Show » 61 7 Yes 0
NRCAM-201 ENSP00000368308
ENST00000379022
B3KRX0
Show all »
Show » Show » 1299 143.3 Yes 1
NRCAM-202 ENSP00000368314
ENST00000379028
Q92823
Show all »
Show » Show » 1304 143.9 Yes 1
NRCAM-203 ENSP00000407858
ENST00000413765
B3KRX0
Show all »
Show » Show » 1211 133.8 Yes 1
NRCAM-204 ENSP00000484840
ENST00000613830
C9JH43
Show all »
Show » Show » 771 85.3 Yes 0