WDR7

GENE INFORMATION

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Gene name

WDR7 (HGNC Symbol)

Synonyms

KIAA0541, TRAG

Description

WD repeat domain 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q21.31

Chromosome location (bp)

56651343 - 57036606

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000091157 (version 78.38)

Entrez gene

23335

UniProt

Q9Y4E6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4E6

Antibodypedia

WDR7 antibodies
 

PROTEIN VIEW

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WDR7-001
 
WDR7-002
 
WDR7-003
 
WDR7-011
 
WDR7-012
 
WDR7-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WDR7-001 ENSP00000254442
ENST00000254442
Q9Y4E6
Show all »
Show » Show » 1490 163.8 No 0
WDR7-002 ENSP00000350187
ENST00000357574
Q9Y4E6
Show all »
Show » Show » 1457 160.5 No 0
WDR7-003 ENSP00000466438
ENST00000593058
K7EMB8
Show all »
Show » Show » 169 18.4 No 0
WDR7-011 ENSP00000466480
ENST00000585669
Show » 40 4.5 No 0
WDR7-012 ENSP00000467485
ENST00000589935
K7EPQ4
Show all »
Show » 67 7.4 No 0
WDR7-201 ENSP00000481823
ENST00000615645
A2RRE0
Show all »
Show » Show » 815 89.3 No 0