CDC6

GENE INFORMATION

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Gene name

CDC6 (HGNC Symbol)

Synonyms

CDC18L

Description

Cell division cycle 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.2

Chromosome location (bp)

40287633 - 40304657

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000094804 (version 78.38)

Entrez gene

990

UniProt

Q99741 (UniProt - Evidence at protein level)

neXtProt

NX_Q99741

Antibodypedia

CDC6 antibodies
 

PROTEIN VIEW

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CDC6-001
 
CDC6-002
 
CDC6-003
 
CDC6-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC6-001 ENSP00000209728
ENST00000209728
Q99741
Show all »
Show » Show » 560 62.7 No 0
CDC6-002 ENSP00000464047
ENST00000473555
J3QR52
Show all »
Show » 118 13.1 No 0
CDC6-003 ENSP00000463635
ENST00000580824
J3QLN7
Show all »
Show » 182 20.4 No 0
CDC6-004 ENSP00000463004
ENST00000577249
J3KTI7
Show all »
Show » 100 11 No 0