FMO2

GENE INFORMATION

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Gene name

FMO2

Synonyms

Description

Flavin containing monooxygenase 2 (non-functional) (HGNC Symbol)

Entrez gene summary

This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Chromosome

1

Cytoband

q24.3

Chromosome location (bp)

171185208 - 171211230

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000094963 (version 78.38)

Entrez gene

2327

UniProt

Q99518 (UniProt - Evidence at protein level)

neXtProt

NX_Q99518

Antibodypedia

FMO2 antibodies
 

PROTEIN VIEW

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FMO2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FMO2-001 ENSP00000209929
ENST00000209929
Q99518
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