DHPS

GENE INFORMATION

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Gene name

DHPS (HGNC Symbol)

Synonyms

MIG13

Description

Deoxyhypusine synthase (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011]

Chromosome

19

Cytoband

p13.13

Chromosome location (bp)

12675717 - 12681902

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000095059 (version 78.38)

Entrez gene

1725

UniProt

P49366 (UniProt - Evidence at protein level)

neXtProt

NX_P49366

Antibodypedia

DHPS antibodies
 

PROTEIN VIEW

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DHPS-001
 
DHPS-003
 
DHPS-006
 
DHPS-008
 
DHPS-016
 
DHPS-017
 
DHPS-021
 
DHPS-022
 
DHPS-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DHPS-001 ENSP00000210060
ENST00000210060
P49366
Show all »
Show » Show » 369 41 No 0
DHPS-003 ENSP00000221303
ENST00000351660
P49366
Show all »
Show » Show » 322 35.9 No 0
DHPS-006 ENSP00000471886
ENST00000594424
P49366
Show all »
Show » Show » 327 36.6 No 0
DHPS-008 ENSP00000471466
ENST00000598246
Show » Show » 159 17.8 No 0
DHPS-016 ENSP00000472094
ENST00000597152
M0R1T2
Show all »
Show » Show » 138 15.6 No 0
DHPS-017 ENSP00000472348
ENST00000596162
M0R264
Show all »
Show » Show » 182 20.7 No 0
DHPS-021 ENSP00000472096
ENST00000600864
M0R1T4
Show all »
Show » Show » 115 12.9 No 0
DHPS-022 ENSP00000469366
ENST00000600639
Show » Show » 27 2.8 No 0
DHPS-201 ENSP00000482709
ENST00000614126
M0R1T2
Show all »
Show » Show » 370 41.1 No 0