CYP26A1

GENE INFORMATION

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Gene name

CYP26A1 (HGNC Symbol)

Synonyms

CP26, CYP26, P450RAI, P450RAI1

Description

Cytochrome P450, family 26, subfamily A, polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q23.33

Chromosome location (bp)

93073475 - 93077890

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000095596 (version 78.38)

Entrez gene

1592

UniProt

O43174 (UniProt - Evidence at protein level)

neXtProt

NX_O43174

Antibodypedia

CYP26A1 antibodies
 

PROTEIN VIEW

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CYP26A1-001
 
CYP26A1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CYP26A1-001 ENSP00000360586
ENST00000371531
O43174
Show all »
Show » Show » 428 48.6 No 0
CYP26A1-002 ENSP00000224356
ENST00000224356
O43174
Show all »
Show » Show » 497 56.2 No 0