BAMBI

GENE INFORMATION

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Gene name

BAMBI (HGNC Symbol)

Synonyms

NMA

Description

BMP and activin membrane-bound inhibitor (HGNC Symbol)

Entrez gene summary

This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p12.1

Chromosome location (bp)

28677342 - 28682939

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000095739 (version 78.38)

Entrez gene

25805

UniProt

Q13145 (UniProt - Evidence at protein level)

neXtProt

NX_Q13145

Antibodypedia

BAMBI antibodies
 

PROTEIN VIEW

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BAMBI-001
 
BAMBI-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BAMBI-001 ENSP00000364683
ENST00000375533
Q13145
Show all »
Show » Show » 260 29.1 Yes 1
BAMBI-201 ENSP00000482033
ENST00000622753
Show » 247 27.8 Yes 1