MADCAM1

GENE INFORMATION

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Gene name

MADCAM1 (HGNC Symbol)

Synonyms

MACAM1

Description

Mucosal vascular addressin cell adhesion molecule 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

489176 - 505343

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099866 (version 78.38)

Entrez gene

8174

UniProt

Q13477 (UniProt - Evidence at protein level)

neXtProt

NX_Q13477

Antibodypedia

MADCAM1 antibodies
 

PROTEIN VIEW

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MADCAM1-001
 
MADCAM1-002
 
MADCAM1-003
 
MADCAM1-004
 
MADCAM1-201
 
MADCAM1-202
 
MADCAM1-203
 
MADCAM1-204
 
MADCAM1-205
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MADCAM1-001 ENSP00000304247
ENST00000346144
Q13477
Show all »
Show » Show » 295 31.1 Yes 1
MADCAM1-002 ENSP00000215637
ENST00000215637
Q13477
Show all »
Show » Show » 382 40.2 Yes 1
MADCAM1-003 ENSP00000372130
ENST00000382683
Q13477
Show all »
Show » Show » 200 21.2 Yes 1
MADCAM1-004 ENSP00000475575
ENST00000587541
U3KQ59
Show all »
Show » 163 17 No 1
MADCAM1-201 ENSP00000480908
ENST00000613880
Show » Show » 406 42.4 Yes 1
MADCAM1-202 ENSP00000484317
ENST00000617201
Show » Show » 400 42.2 Yes 1
MADCAM1-203 ENSP00000484153
ENST00000619333
Show » Show » 398 41.8 Yes 1
MADCAM1-204 ENSP00000483663
ENST00000621286
Show » Show » 400 42.2 Yes 1
MADCAM1-205 ENSP00000480104
ENST00000622462
Show » Show » 390 40.9 Yes 1