SERPIND1

GENE INFORMATION

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Gene name

SERPIND1 (HGNC Symbol)

Synonyms

D22S673, HC-II, HC2, HCF2, HLS2

Description

Serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (HGNC Symbol)

Entrez gene summary

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q11.21

Chromosome location (bp)

20773879 - 20787720

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000099937 (version 78.38)

Entrez gene

3053

UniProt

P05546 (UniProt - Evidence at protein level)

neXtProt

NX_P05546

Antibodypedia

SERPIND1 antibodies
 

PROTEIN VIEW

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SERPIND1-001
 
SERPIND1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SERPIND1-001 ENSP00000215727
ENST00000215727
P05546
Show all »
Show » Show » 499 57.1 Yes 0
SERPIND1-002 ENSP00000384050
ENST00000406799
P05546
Show all »
Show » Show » 499 57.1 Yes 0