GGT1

GENE INFORMATION

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Gene name

GGT1 (HGNC Symbol)

Synonyms

CD224, D22S672, D22S732, GGT

Description

Gamma-glutamyltransferase 1 (HGNC Symbol)

Entrez gene summary

The enzyme encoded by this gene is a type I gamma-glutamyltransferase that catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors. The enzyme is composed of a heavy chain and a light chain, which are derived from a single precursor protein. It is expressed in tissues involved in absorption and secretion and may contribute to the etiology of diabetes and other metabolic disorders. Multiple alternatively spliced variants have been identified. There are a number of related genes present on chromosomes 20 and 22, and putative pseudogenes for this gene on chromosomes 2, 13, and 22. [provided by RefSeq, Jan 2014]

Chromosome

22

Cytoband

q11.23

Chromosome location (bp)

24583750 - 24629005

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100031 (version 78.38)

Entrez gene

2678

UniProt

P19440 (UniProt - Evidence at protein level)

neXtProt

NX_P19440

Antibodypedia

GGT1 antibodies
 

PROTEIN VIEW

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 « 
 
GGT1-001
 
GGT1-002
 
GGT1-003
 
GGT1-004
 
GGT1-005
 
GGT1-010
 
GGT1-011
 
GGT1-012
 
GGT1-013
 
GGT1-014
 
GGT1-015
 
GGT1-016
 
GGT1-017
 
GGT1-018
 
GGT1-019
 
GGT1-020
 
GGT1-023
 
GGT1-024
 
GGT1-025
 
GGT1-026
 
GGT1-027
 
GGT1-028
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGT1-001 ENSP00000383231
ENST00000400380
P19440
Show all »
Show » Show » 569 61.4 Yes 1
GGT1-002 ENSP00000383232
ENST00000400382
P19440
Show all »
Show » Show » 569 61.4 Yes 1
GGT1-003 ENSP00000393537
ENST00000412658
E7ET76
Show all »
Show » Show » 463 50.1 Yes 1
GGT1-004 ENSP00000415553
ENST00000452551
E7ETJ6
Show all »
Show » Show » 127 13.4 Yes 1
GGT1-005 ENSP00000248923
ENST00000248923
P19440
Show all »
Show » Show » 569 61.4 Yes 1
GGT1-010 ENSP00000415129
ENST00000456869
C9JGF3
Show all »
Show » 30 3.2 No 0
GGT1-011 ENSP00000389935
ENST00000411974
E7ENJ5
Show all »
Show » Show » 120 12.6 Yes 1
GGT1-012 ENSP00000393135
ENST00000445029
E9PHP2
Show all »
Show » Show » 68 7.1 Yes 0
GGT1-013 ENSP00000395271
ENST00000419133
E7ETR7
Show all »
Show » Show » 174 18.5 Yes 1
GGT1-014 ENSP00000408151
ENST00000412898
E7ERN9
Show all »
Show » Show » 80 8.3 Yes 0
GGT1-015 ENSP00000415024
ENST00000455483
E7ETN1
Show all »
Show » Show » 98 10.1 Yes 1
GGT1-016 ENSP00000400621
ENST00000447416
E7EM62
Show all »
Show » Show » 126 13.2 Yes 1
GGT1-017 ENSP00000398589
ENST00000432867
E7ETU4
Show all »
Show » Show » 111 11.5 Yes 1
GGT1-018 ENSP00000387796
ENST00000451366
E7EVF8
Show all »
Show » Show » 116 12.1 Yes 1
GGT1-019 ENSP00000403826
ENST00000438643
C9JIY6
Show all »
Show » 37 4 Yes 0
GGT1-020 ENSP00000415068
ENST00000428855
E7EM62
Show all »
Show » Show » 126 13.2 Yes 1
GGT1-023 ENSP00000417044
ENST00000430289
E7ESL5
Show all »
Show » Show » 109 11.4 Yes 1
GGT1-024 ENSP00000384820
ENST00000403838
P19440
Show all »
Show » Show » 225 24.1 No 0
GGT1-025 ENSP00000384381
ENST00000401885
P19440
Show all »
Show » Show » 225 24.1 No 0
GGT1-026 ENSP00000385445
ENST00000404532
P19440
Show all »
Show » Show » 225 24.1 No 0
GGT1-027 ENSP00000385001
ENST00000404920
B5MC36
Show all »
Show » Show » 218 23.6 No 0
GGT1-028 ENSP00000385016
ENST00000404223
B5MC34
Show all »
Show » Show » 252 27 No 0