PHF5A

GENE INFORMATION

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Gene name

PHF5A (HGNC Symbol)

Synonyms

bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7

Description

PHD finger protein 5A (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008]

Chromosome

22

Cytoband

q13.2

Chromosome location (bp)

41459717 - 41468725

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100410 (version 78.38)

Entrez gene

84844

UniProt

Q7RTV0 (UniProt - Evidence at protein level)

neXtProt

NX_Q7RTV0

Antibodypedia

PHF5A antibodies
 

PROTEIN VIEW

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PHF5A-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PHF5A-001 ENSP00000216252
ENST00000216252
Q7RTV0
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