KCNK10

GENE INFORMATION

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Gene name

KCNK10 (HGNC Symbol)

Synonyms

K2p10.1, PPP1R97, TREK-2, TREK2

Description

Potassium channel, subfamily K, member 10 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations, and is stimulated strongly by arachidonic acid and to a lesser degree by membrane stretching, intracellular acidification, and general anaesthetics. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008]

Chromosome

14

Cytoband

q31.3

Chromosome location (bp)

88180103 - 88326907

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100433 (version 78.38)

Entrez gene

54207

UniProt

P57789 (UniProt - Evidence at protein level)

neXtProt

NX_P57789

Antibodypedia

KCNK10 antibodies
 

PROTEIN VIEW

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KCNK10-001
 
KCNK10-002
 
KCNK10-003
 
KCNK10-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNK10-001 ENSP00000343104
ENST00000340700
P57789
Show all »
Show » Show » 538 59.8 Yes 6
KCNK10-002 ENSP00000312811
ENST00000319231
Show » Show » 543 60.3 No 6
KCNK10-003 ENSP00000310568
ENST00000312350
Show » 543 60.1 No 6
KCNK10-004 ENSP00000452587
ENST00000556282
G3V5Y5
Show all »
Show » Show » 157 16.5 No 1