PROCR

GENE INFORMATION

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Gene name

PROCR (HGNC Symbol)

Synonyms

CCD41, CD201, EPCR

Description

Protein C receptor, endothelial (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

35172073 - 35177362

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101000 (version 78.38)

Entrez gene

10544

UniProt

Q9UNN8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNN8

Antibodypedia

PROCR antibodies
 

PROTEIN VIEW

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PROCR-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PROCR-001 ENSP00000216968
ENST00000216968
Q9UNN8
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