CDH20

GENE INFORMATION

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Gene name

CDH20 (HGNC Symbol)

Synonyms

Cdh7, CDH7L3

Description

Cadherin 20, type 2 (HGNC Symbol)

Entrez gene summary

This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q21.33

Chromosome location (bp)

61333582 - 61555773

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101542 (version 78.38)

Entrez gene

28316

UniProt

Q9HBT6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9HBT6

Antibodypedia

CDH20 antibodies
 

PROTEIN VIEW

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CDH20-001
 
CDH20-002
 
CDH20-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH20-001 ENSP00000262717
ENST00000262717
Q9HBT6
Show all »
Show » Show » 801 89 Yes 1
CDH20-002 ENSP00000442226
ENST00000538374
Q9HBT6
Show all »
Show » Show » 801 89 Yes 1
CDH20-201 ENSP00000444767
ENST00000536675
Q9HBT6
Show all »
Show » Show » 801 89 Yes 1