PCDH11X

GENE INFORMATION

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Gene name

PCDH11X (HGNC Symbol)

Synonyms

PCDH-X, PCDH11, PCDHX, PPP1R119

Description

Protocadherin 11 X-linked (HGNC Symbol)

Entrez gene summary

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]

Chromosome

X

Cytoband

q21.31

Chromosome location (bp)

91779261 - 92623230

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000102290 (version 78.38)

Entrez gene

27328

UniProt

Q9BZA7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BZA7

Antibodypedia

PCDH11X antibodies
 

PROTEIN VIEW

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PCDH11X-001
 
PCDH11X-002
 
PCDH11X-003
 
PCDH11X-006
 
PCDH11X-007
 
PCDH11X-008
 
PCDH11X-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PCDH11X-001 ENSP00000362186
ENST00000373094
Q9BZA7
Show all »
Show » Show » 1347 147.6 Yes 1
PCDH11X-002 ENSP00000362189
ENST00000373097
Q9BZA7
Show all »
Show » Show » 1337 146.5 Yes 1
PCDH11X-003 ENSP00000362180
ENST00000373088
Q9BZA7
Show all »
Show » Show » 1310 143.3 Yes 1
PCDH11X-006 ENSP00000423762
ENST00000504220
Q9BZA7
Show all »
Show » Show » 1065 117.6 Yes 1
PCDH11X-007 ENSP00000355105
ENST00000361655
Q9BZA7
Show all »
Show » Show » 1329 145.7 Yes 1
PCDH11X-008 ENSP00000384758
ENST00000406881
Q9BZA7
Show all »
Show » Show » 1339 146.7 Yes 1
PCDH11X-201 ENSP00000378746
ENST00000395337
Show » Show » 1016 112.3 Yes 1