KLF5

GENE INFORMATION

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Gene name

KLF5 (HGNC Symbol)

Synonyms

BTEB2, CKLF, IKLF

Description

Kruppel-like factor 5 (intestinal) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. Expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]

Chromosome

13

Cytoband

q22.1

Chromosome location (bp)

73054976 - 73077542

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102554 (version 78.38)

Entrez gene

688

UniProt

Q13887 (UniProt - Evidence at protein level)

neXtProt

NX_Q13887

Antibodypedia

KLF5 antibodies
 

PROTEIN VIEW

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KLF5-001
 
KLF5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLF5-001 ENSP00000366915
ENST00000377687
Q13887
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Show » Show » 457 50.8 No 0
KLF5-201 ENSP00000440407
ENST00000539231
A2TJX0
Show all »
Show » Show » 366 41.2 No 0