CCL22

GENE INFORMATION

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Gene name

CCL22 (HGNC Symbol)

Synonyms

A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1

Description

Chemokine (C-C motif) ligand 22 (HGNC Symbol)

Entrez gene summary

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]

Chromosome

16

Cytoband

q21

Chromosome location (bp)

57358772 - 57366190

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102962 (version 78.38)

Entrez gene

6367

UniProt

O00626 (UniProt - Evidence at protein level)

neXtProt

NX_O00626

Antibodypedia

CCL22 antibodies
 

PROTEIN VIEW

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CCL22-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL22-001 ENSP00000219235
ENST00000219235
O00626
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