CCL17

GENE INFORMATION

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Gene name

CCL17 (HGNC Symbol)

Synonyms

ABCD-2, SCYA17, TARC

Description

Chemokine (C-C motif) ligand 17 (HGNC Symbol)

Entrez gene summary

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014]

Chromosome

16

Cytoband

q21

Chromosome location (bp)

57404767 - 57416062

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102970 (version 78.38)

Entrez gene

6361

UniProt

Q92583 (UniProt - Evidence at protein level)

neXtProt

NX_Q92583

Antibodypedia

CCL17 antibodies
 

PROTEIN VIEW

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CCL17-001
 
CCL17-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCL17-001 ENSP00000219244
ENST00000219244
Q92583
Show all »
Show » Show » 94 10.5 Yes 0
CCL17-201 ENSP00000480147
ENST00000616880
Q92583
Show all »
Show » Show » 94 10.5 Yes 0