USP10

GENE INFORMATION

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Gene name

USP10 (HGNC Symbol)

Synonyms

KIAA0190, UBPO

Description

Ubiquitin specific peptidase 10 (HGNC Symbol)

Entrez gene summary

Ubiquitin is a highly conserved protein that is covalently linked to other proteins to regulate their function and degradation. This gene encodes a member of the ubiquitin-specific protease family of cysteine proteases. The enzyme specifically cleaves ubiquitin from ubiquitin-conjugated protein substrates. The protein is found in the nucleus and cytoplasm. It functions as a co-factor of the DNA-bound androgen receptor complex, and is inhibited by a protein in the Ras-GTPase pathway. The human genome contains several pseudogenes similar to this gene. Several transcript variants, some protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2013]

Chromosome

16

Cytoband

q24.1

Chromosome location (bp)

84699978 - 84779922

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103194 (version 78.38)

Entrez gene

9100

UniProt

Q14694 (UniProt - Evidence at protein level)

neXtProt

NX_Q14694

Antibodypedia

USP10 antibodies
 

PROTEIN VIEW

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USP10-001
 
USP10-004
 
USP10-008
 
USP10-013
 
USP10-014
 
USP10-015
 
USP10-017
 
USP10-018
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

USP10-001 ENSP00000219473
ENST00000219473
Q14694
Show all »
Show » Show » 798 87.1 No 0
USP10-004 ENSP00000457411
ENST00000570191
Q14694
Show all »
Show » Show » 802 87.5 No 0
USP10-008 ENSP00000458089
ENST00000563892
H3BVF1
Show all »
Show » Show » 158 17.9 No 0
USP10-013 ENSP00000455712
ENST00000562283
H3BQC6
Show all »
Show » Show » 141 15.1 No 0
USP10-014 ENSP00000462762
ENST00000569038
J3KT19
Show all »
Show » Show » 208 23.4 No 0
USP10-015 ENSP00000454751
ENST00000570053
H3BNA1
Show all »
Show » Show » 150 17 No 0
USP10-017 ENSP00000454987
ENST00000569925
Show » 76 8.3 No 0
USP10-018 ENSP00000455865
ENST00000567526
Show » Show » 110 12.4 No 0