MEFV

GENE INFORMATION

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Gene name

MEFV (HGNC Symbol)

Synonyms

FMF, MEF, TRIM20

Description

Mediterranean fever (HGNC Symbol)

Entrez gene summary

This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

p13.3

Chromosome location (bp)

3242028 - 3256627

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103313 (version 78.38)

Entrez gene

4210

UniProt

O15553 (UniProt - Evidence at protein level)

neXtProt

NX_O15553

Antibodypedia

MEFV antibodies
 

PROTEIN VIEW

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MEFV-001
 
MEFV-002
 
MEFV-004
 
MEFV-010
 
MEFV-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MEFV-001 ENSP00000219596
ENST00000219596
O15553
Show all »
Show » Show » 781 86.4 No 0
MEFV-002 ENSP00000438711
ENST00000541159
O15553
Show all »
Show » Show » 445 50.8 No 0
MEFV-004 ENSP00000445079
ENST00000536379
O15553
Show all »
Show » Show » 570 64.5 No 0
MEFV-010 ENSP00000339639
ENST00000339854
F8W6Z2
Show all »
Show » Show » 601 67.7 No 0
MEFV-201 ENSP00000481436
ENST00000621655
I4DSV7
Show all »
Show » Show » 411 47.2 No 0