SLC30A4

GENE INFORMATION

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Gene name

SLC30A4 (HGNC Symbol)

Synonyms

ZNT4

Description

Solute carrier family 30 (zinc transporter), member 4 (HGNC Symbol)

Entrez gene summary

Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008]

Chromosome

15

Cytoband

q21.1

Chromosome location (bp)

45479611 - 45522807

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104154 (version 78.38)

Entrez gene

7782

UniProt

O14863 (UniProt - Evidence at transcript level)

neXtProt

NX_O14863

Antibodypedia

SLC30A4 antibodies
 

PROTEIN VIEW

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SLC30A4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC30A4-001 ENSP00000261867
ENST00000261867
O14863
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