CGB2

GENE INFORMATION

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Gene name

CGB2

Synonyms

Description

Chorionic gonadotropin, beta polypeptide 2 (HGNC Symbol)

Entrez gene summary

The beta subunit of chorionic gonadotropin (CGB) is encoded by six highly homologous and structurally similar genes that are arranged in tandem and inverted pairs on chromosome 19q13.3, and contiguous with the luteinizing hormone beta (LHB) subunit gene. The CGB genes are primarily distinguished by differences in the 5' untranscribed region. This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit, however, detection of CGB1 and CGB2 transcripts in vivo, and their presence on the polysomes, suggested that these transcripts are translated. To date, a protein product corresponding to CGB2 has not been isolated. The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017). However, a 163 aa protein, translated from a different frame, is about the same size, and shares 98% identity with other CGB subunits. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.33

Chromosome location (bp)

49031912 - 49033238

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104818 (version 78.38)

Entrez gene

114336

UniProt

neXtProt

Antibodypedia

CGB2 antibodies
 

PROTEIN VIEW

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CGB2-001
 
CGB2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CGB2-001 ENSP00000471177
ENST00000474913
M0R0E6
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Show » Show » 130 14 No 0
CGB2-002 ENSP00000352295
ENST00000359342
H9KV56
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Show » Show » 163 17.4 Yes 0