NFKBIB

GENE INFORMATION

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Gene name

NFKBIB (HGNC Symbol)

Synonyms

IKBB, TRIP9

Description

Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

38899700 - 38908893

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104825 (version 78.38)

Entrez gene

4793

UniProt

Q15653 (UniProt - Evidence at protein level)

neXtProt

NX_Q15653

Antibodypedia

NFKBIB antibodies
 

PROTEIN VIEW

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NFKBIB-001
 
NFKBIB-002
 
NFKBIB-004
 
NFKBIB-005
 
NFKBIB-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFKBIB-001 ENSP00000459728
ENST00000572515
Q15653
Show all »
Show » Show » 338 35.5 No 0
NFKBIB-002 ENSP00000312988
ENST00000313582
Q15653
Show all »
Show » Show » 356 37.8 No 0
NFKBIB-004 ENSP00000461617
ENST00000576510
I3L4X3
Show all »
Show » Show » 234 25.2 No 0
NFKBIB-005 ENSP00000458685
ENST00000575359
I3L1A4
Show all »
Show » Show » 149 16.5 No 0
NFKBIB-201 ENSP00000375929
ENST00000392079
I3L4X3
Show all »
Show » Show » 270 29.1 No 0