AKAP8

GENE INFORMATION

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Gene name

AKAP8 (HGNC Symbol)

Synonyms

AKAP95, DKFZp586B1222

Description

A kinase (PRKA) anchor protein 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]

Chromosome

19

Cytoband

p13.12

Chromosome location (bp)

15353385 - 15379798

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105127 (version 78.38)

Entrez gene

10270

UniProt

O43823 (UniProt - Evidence at protein level)

neXtProt

NX_O43823

Antibodypedia

AKAP8 antibodies
 

PROTEIN VIEW

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AKAP8-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AKAP8-004 ENSP00000269701
ENST00000269701
O43823
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