RPS19

GENE INFORMATION

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Gene name

RPS19 (HGNC Symbol)

Synonyms

DBA, S19

Description

Ribosomal protein S19 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

41859918 - 41872926

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105372 (version 78.38)

Entrez gene

6223

UniProt

P39019 (UniProt - Evidence at protein level)

neXtProt

NX_P39019

Antibodypedia

RPS19 antibodies
 

PROTEIN VIEW

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RPS19-001
 
RPS19-002
 
RPS19-003
 
RPS19-005
 
RPS19-006
 
RPS19-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPS19-001 ENSP00000470972
ENST00000598742
P39019
Show all »
Show » Show » 145 16.1 No 0
RPS19-002 ENSP00000469228
ENST00000600467
M0QXK4
Show all »
Show » Show » 76 8.5 No 0
RPS19-003 ENSP00000471621
ENST00000601492
M0R140
Show all »
Show » Show » 102 11.1 No 0
RPS19-005 ENSP00000221975
ENST00000221975
A0A075B6E2
Show all »
Show » Show » 71 7.8 No 0
RPS19-006 ENSP00000470004
ENST00000593863
P39019
Show all »
Show » Show » 145 16.1 No 0
RPS19-007 ENSP00000469798
ENST00000598261
M0QYF7
Show all »
Show » Show » 100 11.6 No 0