KLF1

GENE INFORMATION

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Gene name

KLF1 (HGNC Symbol)

Synonyms

EKLF

Description

Kruppel-like factor 1 (erythroid) (HGNC Symbol)

Entrez gene summary

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]

Chromosome

19

Cytoband

p13.13

Chromosome location (bp)

12884423 - 12887181

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105610 (version 78.38)

Entrez gene

10661

UniProt

Q13351 (UniProt - Evidence at protein level)

neXtProt

NX_Q13351

Antibodypedia

KLF1 antibodies
 

PROTEIN VIEW

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KLF1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLF1-001 ENSP00000264834
ENST00000264834
Q13351
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