GAPDHS

GENE INFORMATION

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Gene name

GAPDHS (HGNC Symbol)

Synonyms

GAPD2, GAPDH-2, GAPDS

Description

Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (HGNC Symbol)

Entrez gene summary

This gene encodes a protein belonging to the glyceraldehyde-3-phosphate dehydrogenase family of enzymes that play an important role in carbohydrate metabolism. Like its somatic cell counterpart, this sperm-specific enzyme functions in a nicotinamide adenine dinucleotide-dependent manner to remove hydrogen and add phosphate to glyceraldehyde 3-phosphate to form 1,3-diphosphoglycerate. During spermiogenesis, this enzyme may play an important role in regulating the switch between different energy-producing pathways, and it is required for sperm motility and male fertility. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

q13.12

Chromosome location (bp)

35533412 - 35545316

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105679 (version 78.38)

Entrez gene

26330

UniProt

O14556 (UniProt - Evidence at protein level)

neXtProt

NX_O14556

Antibodypedia

GAPDHS antibodies
 

PROTEIN VIEW

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GAPDHS-001
 
GAPDHS-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GAPDHS-001 ENSP00000222286
ENST00000222286
O14556
Show all »
Show » Show » 408 44.5 No 0
GAPDHS-004 ENSP00000467255
ENST00000585510
K7EP73
Show all »
Show » Show » 179 19.6 No 0