DNAJC2

GENE INFORMATION

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Gene name

DNAJC2 (HGNC Symbol)

Synonyms

MPHOSPH11, MPP11, ZRF1, ZUO1, zuotin

Description

DnaJ (Hsp40) homolog, subfamily C, member 2 (HGNC Symbol)

Entrez gene summary

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

103312474 - 103344873

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105821 (version 78.38)

Entrez gene

27000

UniProt

Q99543 (UniProt - Evidence at protein level)

neXtProt

NX_Q99543

Antibodypedia

DNAJC2 antibodies
 

PROTEIN VIEW

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DNAJC2-001
 
DNAJC2-002
 
DNAJC2-003
 
DNAJC2-010
 
DNAJC2-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNAJC2-001 ENSP00000368565
ENST00000379263
Q99543
Show all »
Show » Show » 621 72 No 0
DNAJC2-002 ENSP00000249270
ENST00000249270
Q99543
Show all »
Show » Show » 568 65.9 No 0
DNAJC2-003 ENSP00000406275
ENST00000412522
F2Z3H0
Show all »
Show » 118 13.5 No 0
DNAJC2-010 ENSP00000399058
ENST00000454277
C9IZ83
Show all »
Show » Show » 188 22.4 No 0
DNAJC2-011 ENSP00000412611
ENST00000426036
Show » 243 28.5 No 0