TFPI2

GENE INFORMATION

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Gene name

TFPI2 (HGNC Symbol)

Synonyms

PP5, REF1, TFPI-2

Description

Tissue factor pathway inhibitor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Kunitz-type serine proteinase inhibitor family. The protein can inhibit a variety of serine proteases including factor VIIa/tissue factor, factor Xa, plasmin, trypsin, chymotryspin and plasma kallikrein. This gene has been identified as a tumor suppressor gene in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

7

Cytoband

q21.3

Chromosome location (bp)

93885397 - 93890991

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105825 (version 78.38)

Entrez gene

7980

UniProt

P48307 (UniProt - Evidence at protein level)

neXtProt

NX_P48307

Antibodypedia

TFPI2 antibodies
 

PROTEIN VIEW

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TFPI2-001
 
TFPI2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFPI2-001 ENSP00000222543
ENST00000222543
P48307
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Show » Show » 235 26.9 Yes 0
TFPI2-003 ENSP00000416370
ENST00000451238
H7C4A3
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Show » Show » 107 12 No 0