TFR2

GENE INFORMATION

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Gene name

TFR2 (HGNC Symbol)

Synonyms

HFE3, TFRC2

Description

Transferrin receptor 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a single-pass type II membrane protein, which is a member of the transferrin receptor-like family. This protein mediates cellular uptake of transferrin-bound iron, and may be involved in iron metabolism, hepatocyte function and erythrocyte differentiation. Mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]

Chromosome

7

Cytoband

q22.1

Chromosome location (bp)

100620416 - 100642779

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106327 (version 78.38)

Entrez gene

7036

UniProt

Q9UP52 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UP52

Antibodypedia

TFR2 antibodies
 

PROTEIN VIEW

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TFR2-001
 
TFR2-201
 
TFR2-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFR2-001 ENSP00000420525
ENST00000462107
Q9UP52
Show all »
Show » Show » 801 88.8 No 1
TFR2-201 ENSP00000223051
ENST00000223051
Q9UP52
Show all »
Show » Show » 801 88.8 No 1
TFR2-202 ENSP00000413905
ENST00000431692
E7ET36
Show all »
Show » 355 39.5 No 1