RHEB

GENE INFORMATION

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Gene name

RHEB (HGNC Symbol)

Synonyms

RHEB2

Description

Ras homolog enriched in brain (HGNC Symbol)

Entrez gene summary

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q36.1

Chromosome location (bp)

151466012 - 151520120

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106615 (version 78.38)

Entrez gene

6009

UniProt

Q15382 (UniProt - Evidence at protein level)

neXtProt

NX_Q15382

Antibodypedia

RHEB antibodies
 

PROTEIN VIEW

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RHEB-001
 
RHEB-002
 
RHEB-003
 
RHEB-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RHEB-001 ENSP00000262187
ENST00000262187
Q15382
Show all »
Show » Show » 184 20.5 No 0
RHEB-002 ENSP00000418161
ENST00000496004
C9J931
Show all »
Show » Show » 79 8.7 No 0
RHEB-003 ENSP00000420726
ENST00000472642
C9J931
Show all »
Show » Show » 79 8.7 No 0
RHEB-007 ENSP00000417212
ENST00000470370
Show » 19 2.1 No 0