CUBN

GENE INFORMATION

? »

Gene name

CUBN (HGNC Symbol)

Synonyms

gp280, IFCR, MGA1

Description

Cubilin (intrinsic factor-cobalamin receptor) (HGNC Symbol)

Entrez gene summary

Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p13

Chromosome location (bp)

16823964 - 17129831

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107611 (version 78.38)

Entrez gene

8029

UniProt

O60494 (UniProt - Evidence at protein level)

neXtProt

NX_O60494

Antibodypedia

CUBN antibodies
 

PROTEIN VIEW

? »
 
 
 
CUBN-001
 
CUBN-002
 
CUBN-003
 
CUBN-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CUBN-001 ENSP00000367064
ENST00000377833
O60494
Show all »
Show » Show » 3623 398.7 Yes 0
CUBN-002 ENSP00000391830
ENST00000438254
Q5JQ33
Show all »
Show » 88 9.7 No 0
CUBN-003 ENSP00000367054
ENST00000377823
B0YIZ6
Show all »
Show » Show » 170 19.2 Yes 0
CUBN-004 ENSP00000415970
ENST00000433666
H7C480
Show all »
Show » Show » 105 11.6 No 0