MICU1

GENE INFORMATION

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Gene name

MICU1 (HGNC Symbol)

Synonyms

CALC, CBARA1, EFHA3, FLJ12684

Description

Mitochondrial calcium uptake 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]

Chromosome

10

Cytoband

q22.1

Chromosome location (bp)

72367327 - 72626191

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107745 (version 78.38)

Entrez gene

10367

UniProt

Q9BPX6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BPX6

Antibodypedia

MICU1 antibodies
 

PROTEIN VIEW

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MICU1-002
 
MICU1-004
 
MICU1-005
 
MICU1-006
 
MICU1-010
 
MICU1-012
 
MICU1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MICU1-002 ENSP00000354415
ENST00000361114
Q9BPX6
Show all »
Show » Show » 476 54.4 No 0
MICU1-004 ENSP00000402470
ENST00000418483
Q9BPX6
Show all »
Show » Show » 278 32.1 No 0
MICU1-005 ENSP00000381747
ENST00000398763
Q9BPX6
Show all »
Show » Show » 278 31.9 No 0
MICU1-006 ENSP00000474192
ENST00000603011
S4R3D7
Show all »
Show » Show » 212 24.1 Yes 0
MICU1-010 ENSP00000474775
ENST00000604238
S4R3V1
Show all »
Show » 213 24.5 No 0
MICU1-012 ENSP00000474809
ENST00000489666
S4R3W3
Show all »
Show » Show » 154 18 No 0
MICU1-201 ENSP00000381745
ENST00000398761
Show » Show » 478 54.6 No 0