ACTA2

GENE INFORMATION

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Gene name

ACTA2 (HGNC Symbol)

Synonyms

ACTSA

Description

Actin, alpha 2, smooth muscle, aorta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]

Chromosome

10

Cytoband

q23.31

Chromosome location (bp)

88935074 - 88991390

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107796 (version 78.38)

Entrez gene

59

UniProt

P62736 (UniProt - Evidence at protein level)

neXtProt

NX_P62736

Antibodypedia

ACTA2 antibodies
 

PROTEIN VIEW

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ACTA2-001
 
ACTA2-002
 
ACTA2-003
 
ACTA2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACTA2-001 ENSP00000224784
ENST00000224784
P62736
Show all »
Show » Show » 377 42 No 0
ACTA2-002 ENSP00000396730
ENST00000415557
F6QUT6
Show all »
Show » 151 16.8 No 0
ACTA2-003 ENSP00000398239
ENST00000458159
F6QUT6
Show all »
Show » 151 16.8 No 0
ACTA2-201 ENSP00000402373
ENST00000458208
P62736
Show all »
Show » Show » 377 42 No 0