GTPBP4

GENE INFORMATION

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Gene name

GTPBP4 (HGNC Symbol)

Synonyms

CRFG, FLJ10686, FLJ10690, NGB, NOG1

Description

GTP binding protein 4 (HGNC Symbol)

Entrez gene summary

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p15.3

Chromosome location (bp)

988019 - 1019936

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107937 (version 78.38)

Entrez gene

23560

UniProt

Q9BZE4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZE4

Antibodypedia

GTPBP4 antibodies
 

PROTEIN VIEW

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GTPBP4-001
 
GTPBP4-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GTPBP4-001 ENSP00000354040
ENST00000360803
Q9BZE4
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Show » Show » 634 74 No 0
GTPBP4-006 ENSP00000353168
ENST00000360059
Q5T3R7
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Show » 140 16.5 No 0