CASC3

GENE INFORMATION

? »

Gene name

CASC3 (HGNC Symbol)

Synonyms

BTZ, MLN51

Description

Cancer susceptibility candidate 3 (HGNC Symbol)

Entrez gene summary

The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.1

Chromosome location (bp)

40140318 - 40172183

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108349 (version 78.38)

Entrez gene

22794

UniProt

O15234 (UniProt - Evidence at protein level)

neXtProt

NX_O15234

Antibodypedia

CASC3 antibodies
 

PROTEIN VIEW

? »
 
 
 
CASC3-001
 
CASC3-007
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CASC3-001 ENSP00000264645
ENST00000264645
O15234
Show all »
Show » Show » 703 76.3 No 0
CASC3-007 ENSP00000467654
ENST00000584997
K7EQ38
Show all »
Show » 66 7.2 No 0