MED13

GENE INFORMATION

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Gene name

MED13 (HGNC Symbol)

Synonyms

KIAA0593, THRAP1, TRAP240

Description

Mediator complex subunit 13 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q23.2

Chromosome location (bp)

61942605 - 62065282

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108510 (version 78.38)

Entrez gene

9969

UniProt

Q9UHV7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHV7

Antibodypedia

MED13 antibodies
 

PROTEIN VIEW

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MED13-001
 
MED13-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MED13-001 ENSP00000380888
ENST00000397786
Q9UHV7
Show all »
Show » Show » 2174 239.3 No 0
MED13-003 ENSP00000464131
ENST00000583958
Q9P0Q5
Show all »
Show » 327 36.4 No 0