NUP88

GENE INFORMATION

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Gene name

NUP88 (HGNC Symbol)

Synonyms

MGC8530

Description

Nucleoporin 88kDa (HGNC Symbol)

Entrez gene summary

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.2

Chromosome location (bp)

5360963 - 5420160

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108559 (version 78.38)

Entrez gene

4927

UniProt

Q99567 (UniProt - Evidence at protein level)

neXtProt

NX_Q99567

Antibodypedia

NUP88 antibodies
 

PROTEIN VIEW

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NUP88-001
 
NUP88-004
 
NUP88-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NUP88-001 ENSP00000458954
ENST00000573584
Q99567
Show all »
Show » Show » 741 83.5 No 0
NUP88-004 ENSP00000225696
ENST00000225696
B4DP20
Show all »
Show » 696 78.8 No 0
NUP88-006 ENSP00000459370
ENST00000572809
I3L245
Show all »
Show » 153 16.9 No 0